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Big Brain Holdings

Big Brain Holdings

Venture Capital
Est. Jan 1, 2021154 investments

Big Brain Holdings is a crypto-exclusive fund investing in pre-seed, seed, and early-stage projects. We believe in a crypto-forward future and invest in teams paving the way towards that future. The team focuses on projects that are unique, innovative, and on the cutting edge of blockchain. Big Brain Holdings values long-term partnerships and helps the projects we invest in grow and prosper through our various value-added benefits.

Portfolio

154
NEAR Intents
NEAR Intents

Multi-chain financial product protocols

Funding
Angular Finance
Angular Finance

A cross-chain Lending market

Funding
Shil.me
Shil.me

---

Funding
VCRED
VCRED

Disrupting deFi through automation

Funding
Royale Chess
Royale Chess

Chess Battle Royale game

Funding
Valhalla
Valhalla

The Perpetuals Exchange on MegaETH

Funding
Dust Labs
Dust Labs

The firm behind popular NFT projects DeGods and y00ts

Funding
Load Network
Load Network

The hyperscalable EVM protocol on Arweave

Funding
Cube.Exchange
Cube.Exchange

Hybrid Crypto Trading Platform

Funding
Mayan
Mayan

Cross-chain Swap Auction Protocol

Funding
Atocha Protocol
Atocha Protocol

A web3 puzzle game protocol

Funding
Helius
Helius

Solana developer platform

Funding
The New Computer Corporation
The New Computer Corporation

Web3 product studio

Funding
zkLink
zkLink

Trading-focused multi-chain L2 network

Strategic$10.0MJul 2024
Lighthouse.Storage
Lighthouse.Storage

---

Funding
Oh
Oh

AI infrastructure and products for digital creators

Funding
PlayEmber
PlayEmber

Mobile game studio

Funding
Youmio
Youmio

Social sandbox game

Seed$5.0MApr 2024
Unique Venture Clubs
Unique Venture Clubs

Democratizing investing and asset management

Funding
Kaidro
Kaidro

Post-apocalyptic sci-fi universe

Funding$5.0MApr 2023
Artela Network
Artela Network

L1 blockchain with parallel execution

Seed$6.0MJul 2023
ZKasino
ZKasino

Decentralized Casino

Funding
Dante Network
Dante Network

General middle layer

Funding
HaloFi
HaloFi

A decentralized savings pool which rewards regular saving

Funding
Haiku
Haiku

On-chain intent trading protocol

Funding
GARD
GARD
Funding
legend.trade
legend.trade

Telegram-based trading and matchmaking platforms

Funding
Stackup
Stackup

Learn-and-Earn Platform

Funding
Sphere
Sphere

Payments infrastructure for crypto

Funding
HypeLab
HypeLab

Web3 ad network

Funding
MatchboxDAO
MatchboxDAO

Starkware-based on-chain gaming ecosystem

Funding
Panzerdogs / WAGMI
Panzerdogs / WAGMI

Solana NFT gaming project

Funding
Eclipse Fi
Eclipse Fi

Modular launch and liquidity solution

Funding$1.9MDec 2023
BitRobot
BitRobot

Solana-based Crypto AI Incentive Platform

Funding
Nimblr
Nimblr

Decentralized insurance platform

Funding
IVX
IVX

Options AMM for crypto assets

Funding
Tamago
Tamago

Decentralized audio streaming platform

Funding
Outdefine
Outdefine

A decentralized talent community

Funding
WayRu
WayRu

Decentralized Internet Network

Funding
Solana
Solana

High performance underlying blockchain

Funding$314.0MJun 2021
Algomint
Algomint

Bringing BTC, ETH & stablecoins to Algorand

Funding
Loopscale
Loopscale

Borrowing and lending platform on Solana

Seed$4.3MDec 2021
Marinade Finance
Marinade Finance

Liquid Staking Protocol on Solana

Funding
TsunamiX
TsunamiX

Margin trading and spot exchange

Funding
BitFlow
BitFlow

Decentralized Exchange

Funding
Ambient
Ambient

SVM-compatible Proof of Work L1

Funding
Arch Network
Arch Network

Bitcoin-Native Application Platform

Series A$13.0MApr 2025
Battle Drones
Battle Drones

Top-down drone shooter

Funding
ChainScore
ChainScore

Decentralized credit scoring protocol

Funding
Chillchat
Chillchat

Pixel art NFT metaverse

Seed$6.5MJun 2022
Crema Finance
Crema Finance

Concentrated liquidity protocol

Private$5.5MJun 2022
Crossmint
Crossmint

A technology company focused on blockchain infrastructure

Funding$23.6MMar 2025
Deepwaters
Deepwaters

A system of decentralized finance (DeFi) applications

Funding
Fableborne / Pixion Games
Fableborne / Pixion Games

Isometric play-to-own multiplayer game

Funding
Parallel
Parallel

Sci-Fi Franchise and Card Game

Funding$35.0MMar 2024
Steer Protocol
Steer Protocol

Multi-chain decentralized keeper network

Funding
Vertex Protocol
Vertex Protocol

Decentralized derivatives protocol

Seed$8.5MApr 2022
Vest Exchange
Vest Exchange

Universal risk pricing infrastructure

Funding
Openfabric AI
Openfabric AI

Layer 1 for Artificial Intelligence

Seed$500KNov 2022
Helika
Helika

Web3 gaming and NFT analytics platform

Funding
Sui Group Holdings
Sui Group Holdings

Non-bank lenders (NASDAQ: SUIG)

Funding
Aperture Finance
Aperture Finance

AI-powered Intent Based Infrastructure

Series A$6.7MMay 2024
LuminaDEX
LuminaDEX

Decentralized Exchange

Funding
Optimum
Optimum

High-performance memory infrastructure

Funding
Sphinx
Sphinx

RWAs perpetuals protocol

Funding
GLIF
GLIF

Filecoin’s premier staking protocol

Funding
Jump DeFi
Jump DeFi

One-stop DeFi platform

Funding
Safary
Safary

Marketing stack in web3

Funding
Inference Labs
Inference Labs

Web3 AI Infrastructure

Funding
AVNU
AVNU

Decentralized trading protocol

Funding
Planet Mojo
Planet Mojo

A web3 gaming metaverse

Strategic$5.5MApr 2024
ULTRADE
ULTRADE

Multichain DeFi-as-a-Service infrastructure company

Funding
SolStreet
SolStreet

---

Funding
Fanfury
Fanfury

Fantasy Sports World

Funding
PortalVerse
PortalVerse

Decentralized cloud gaming network

Funding
FrodoBots
FrodoBots

Open-world game

Funding
Outlet Finance
Outlet Finance

Crypto Wallet

Funding
GYRIS
GYRIS

NFT Saga MMORPG

Funding
M10
M10

Blockchain gaming platform

Funding
Gora Network
Gora Network

Oracle network

Seed$1.5MMay 2022
Utila
Utila

Self-custody wallet platform and API

Funding
Nubit
Nubit

Bitcoin boosting network

Seed$8.0MJun 2024
Decent.land
Decent.land

Identity and social on Arweave

Funding
Cookie3
Cookie3

MarketingFi platforms

Funding
Fortytwo
Fortytwo

Multi-agent AI protocol

Funding
Essential
Essential

Intent-based infrastructure & tooling

Funding
Watch.fun
Watch.fun

Luxury watch platform

Funding
AID:Tech
AID:Tech

On-chain reputation & rewards for Web3

Funding
kash
kash

Prediction market protocol

Funding
Minteo
Minteo

Latin American NFT marketplace

Funding
SYNO
SYNO

Universal cross-chain credit layer

Seed$1.5MJan 2024
Footium
Footium

Multiplayer football management game

Funding
Exchange Art
Exchange Art

Fine art marketplace on Solana

Seed$3.2MSep 2022
Photo Finish
Photo Finish

Play-to-earn virtual horse racing ecosystem

Funding
Homespace
Homespace

Decentralized NFT Metaverse with Architecture and Artificial Intelligence

Funding
Zoo Finance
Zoo Finance

Native Liquidity Structured Protocol

Funding
TipLink
TipLink

Lightweight wallet

Funding
Pixelverse
Pixelverse

Cyberpunk fighting game

Funding$2.0MJul 2024
NEAR Protocol
NEAR Protocol

Layer-one blockchain

Funding$350.0MApr 2022
Monad
Monad

High-performance layer 1 blockchain

Funding$188.0MNov 2025
Avalanche
Avalanche

Decentralized blockchain

Funding
Sui
Sui

Layer 1 blockchain

Series B$300.0MSep 2022
Sonic
Sonic

Layer-1 platform

Series A$12.0MJun 2024
Aethir
Aethir

Decentralized enterprise-level GPU cloud network

Funding$9.0MJul 2023
Pudgy Penguins
Pudgy Penguins

Penguin NFT Ecosystem

Seed$9.0MMay 2023
Sweatcoin
Sweatcoin

Move-to-Earn app

Funding$13.0MJul 2022
Grass
Grass

Network sharing application

Seed$3.5MDec 2023
Cosmos
Cosmos

The Internet of Blockchains

Series A$9.0MMar 2019
Kima
Kima

The Universal Blockchain Settlement Layer

Pre-Seed$5.0MJun 2024
Mind Network
Mind Network

Fully encrypted web3 infrastructure with FHE

Funding$10.0MSep 2024
Star Atlas
Star Atlas

Next-gen gaming metaverse

Funding
The Graph
The Graph

Decentralized protocol for indexing and querying blockchain data

Funding$50.0MJan 2022
DIN
DIN

AI Agent Blockchain

Seed$4.0MApr 2025
Perle Labs
Perle Labs

Data for AI training

Seed$9.0MAug 2025
Hemi
Hemi

Modular Layer 2 network

Funding$15.0MAug 2025
MegaETH
MegaETH

Ultra high-performance real-time EVM L2

Community$10.0MDec 2024
Nillion
Nillion

Decentralized public network

Funding$25.0MOct 2024
Dymension
Dymension

Modular settlement layer

Seed$6.7MFeb 2023
Secret Network
Secret Network

Private blockchain network based on Cosmos SDK

ICO$45.0MMay 2021
Zeus Network
Zeus Network

Permissionless Communication Layer on Solana and Bitcoin

Funding$8.0MApr 2024
Affyn
Affyn

Geolocation-based metaverse that converges the virtual and real world

Funding
Solayer
Solayer

Hardware-accelerated restaking network on Solana

Community$10.5MJan 2025
Fly
Fly

Aggregation infra for DEXs, LSTs and chains

IDO$1.6MMar 2025
Walken
Walken

Move-to-earn game

Funding
Natix Network
Natix Network

Decentralised network of cameras

Funding$5.0MMay 2024
Aark Digital
Aark Digital

Decentralized derivatives exchange

Funding
Suilend
Suilend

DeFi on Sui starts with Suilend

Funding$4.0MDec 2024
BIO Protocol
BIO Protocol

Financial layer for DeSci

Seed$6.9MSep 2025
Ten
Ten

Layer 2 Blockchain Privacy Protocol

Funding$9.0MMar 2024
Arweave
Arweave

Decentralized Data Storage Protocol

Funding$8.3MMar 2020
Oasys
Oasys

The blockchain optimized for gamers

Private$20.0MJul 2022
Chia
Chia

Blockchain and smart transaction platform

Series D$61.0MMay 2021
Thala
Thala

Aptos-native DeFi with stablecoin and AMM

IDO$3.0MApr 2023
Soil
Soil

DeFi infrastructure backed by RWA

Funding
Collector
Collector

Bridges real world collectibles onto the blockchain

Funding
Mavryk Network
Mavryk Network

RWA tokenization platform

Funding$10.0MSep 2025
SatLayer
SatLayer

Bitcoin restaking platform

Pre-Seed$8.0MAug 2024
Shiba Inu
Shiba Inu

Decentralized meme token

Funding$12.0MApr 2024
Convergence
Convergence

The decentralized interchangeable assets protocol

Funding
STIX
STIX

OTC platform for the digital asset

Funding
Banx
Banx

NFT lending protocol

Funding
Tensor
Tensor

Solana's Leading NFT Marketplace

Seed$3.0MApr 2024
Ranger
Ranger

Decentralized trading platform

Funding$1.9MJan 2025
octra
octra

Universal FHE protocol

Pre-Seed$4.0MSep 2024
JPool
JPool

Stake pools on the Solana blockchain network

Funding
Arcade
Arcade

Marketplace for peer-to-peer commerce

Funding$4.8MJan 2024
Initia
Initia

Omnichain rollups

Community$2.5MSep 2024
Saturn
Saturn

Non-custodial peer-to-peer orderbook

Funding
Sanctum
Sanctum

Solana 's LSD Protocol

Seed$350KApr 2024
Reflect
Reflect

Synthetic Currency Exchange Protocol

Funding
Aria
Aria

Combining RWA and IP platform

Funding$5.0MJul 2025
DRiP
DRiP

Creator platform on the Solana

Funding
Hedge
Hedge

Solana lending protocol

Funding
Arcium
Arcium

Parallelized confidential computing network

Community$1.0MMar 2025

News

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honestly you probably should follow @solana on tiktok → https://www.tiktok.com/@solana

@solanaMay 2026

The hottest spot in SF is about to get even hotter. Join @solana_devs at the @UseCorgi Cafe on June 1st for for a builder happy hour with drinks and pastries on us. ​Open to developers, founders, and technologists building at the edge of new markets.

@solanaMay 2026

The next GRASS Token Holder and Network Participant Call will take place on July 7. The call will provide an overview of Grass network progress, the development roadmap, business milestones, growth highlights, and more. To promote equal access to information, the call will be open to the public. Qu

@grassMay 2026

Voting has a new venue in Nepal. 8k+ voters and counting on Solana. Watch the full story behind @janamatnp 🇳🇵 https://x.com/janamatnp/status/2059678553315463578

@solanaMay 2026

RT @shefiorg: She's finally here. ✨ For the first time in SheFi's history, we're joined by @Solana. One of the most powerful ecosystems i…

@SolanaFndnMay 2026

Monad daily stats | May 27

@monscope_xyzMay 2026

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@defimarketsMay 2026

Watch @Solana become the #1 chain for trading volume over the years 🚀

@solanaMay 2026

Creating apps that use real assets on Solana, like TSLA or BTC, is complicated. Meet the @tokens Assets API, now open to all. In use already by 90+ products including @Phantom and @DFlow, builders can leverage a single trustworthy asset layer.

@solanaMay 2026